Casual Fridays — what makes a great resume? [Cognitive Daily]

February 27, 2009 in Blogs, Brain & Behaviour by BrainAndBehaviour

There’s a lot of advice online about what makes a good resume, and in these tough economic times, getting a job is tougher than ever. So this week, I thought we’d test some different resumes and see which factors are most important in picking a good candidate. You’ll be asked to read two resumes very carefully, then answer a few questions evaluating each candidate. I’ve changed just a few items on each resume, so make sure you read them closely. Then next week we’ll see which factors matter the most. Click here to participate As usual, the study has just a few questions, and should only take a few minutes to complete. There is no limit on the number of respondents. You’ll have until Thursday, March 5 to complete your response. Don’t forget to come back next Friday for the results! Read the comments on this post…

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Casual Fridays — what makes a great resume? [Cognitive Daily]

Improved Learning and Memory in Aged Mice Deficient in Amyloid β-Degrading Neutral Endopeptidase

February 25, 2009 in Blogs, Plosone - Neuroscience by PLSOne - Neuroscience

Background Neutral endopeptidase, also known as neprilysin and abbreviated NEP, is considered to be one of the key enzymes in initial human amyloid-β (Aβ) degradation. The aim of our study was to explore the impact of NEP deficiency on the initial development of dementia-like symptoms in mice. Methodology/Principal Findings We found that while endogenous Aβ concentrations were elevated in the brains of NEP-knockout mice at all investigated age groups, immunohistochemical analysis using monoclonal antibodies did not detect any Aβ deposits even in old NEP knockout mice. Surprisingly, tests of learning and memory revealed that the ability to learn was not reduced in old NEP-deficient mice but instead had significantly improved, and sustained learning and memory in the aged mice was congruent with improved long-term potentiation (LTP) in brain slices of the hippocampus and lateral amygdala. Our data suggests a beneficial effect of pharmacological inhibition of cerebral NEP on learning and memory in mice due to the accumulation of peptides other than Aβ degradable by NEP. By conducting degradation studies and peptide measurements in the brain of both genotypes, we identified two neuropeptide candidates, glucagon-like peptide 1 and galanin, as first potential candidates to be involved in the improved learning in aged NEP-deficient mice. Conclusions/Significance Thus, the existence of peptides targeted by NEP that improve learning and memory in older individuals may represent a promising avenue for the treatment of neurodegenerative diseases.

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Improved Learning and Memory in Aged Mice Deficient in Amyloid β-Degrading Neutral Endopeptidase

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How to Choose Between Experiential and Material Purchases

February 23, 2009 in Blogs, PsyBlog by PsyBlog

If you decided to spend $100 on your happiness, would you buy something experiential like a meal out or something material like an item of clothing? Research covered here recently suggested that for long-term happiness experiences tend to beat possessions . But Leonardo Nicolao and colleagues at the University of Texas argue in the Journal of Consumer Research that this research doesn’t tell us the whole picture ( Nicolao et al., 2009 ). Nicolao and colleagues point out that the previous research by Van Boven and Gilovich (2003) only compared experiential and material purchases that went well, not those that went wrong. What if the clothes turn out to be money down the drain or the meal out is a complete bust from beginning to end: what does that do to our happiness? When purchases go wrong The researchers used three experiments to examine this question. In the first two of these participants were randomly assigned to groups in which they recalled material and experiential purchases that had either turned out well, or that had turned out badly. They were then asked how happy (or otherwise) these purchases had made them. The results suggested that, just like Van Boven and Gilovich’s research, experiential purchases (e.g. a meal out) beat material purchases (e.g. clothes) if each turned out well. But, for some people whose scores were low on a measure of materialism, when the purchases turned out badly, it was the material goods that left them slightly happier. In contrast the highly materialistic were left less happy when their material purchases went wrong. In a third experiment participants actually made a small experiential versus a small material purchase and then their happiness over time was measured. It was found that when participants made a material purchase that turned out badly it was easier for them to forget about it than an experiential purchase that went wrong. Across three experiments, then, Nicolao and colleagues found evidence that when our experiential purchases go wrong we are likely to end up slightly less happy than if we had chosen a material purchase. But, as in previous research, when our purchases go well we are likely to end up significantly happier if we choose an experiential rather than a material purchase. Experiences still beat possessions This study provides further support for the idea that experiential purchases like restaurant trips or theatre tickets are likely to beat material purchases like clothes or electronics for our long-term happiness. Nicolao and colleagues show that this is at least partly because it takes us longer to adapt to experiential purchases than material purchases. Experiences also beat possessions because they seem to: Improve with time as we forget about all the boring moments and just recall the highlights. Take on symbolic meanings, whereas those shoes are still just shoes. Be very resistant to unfavourable comparisons: a wonderful moment in a restaurant is personally yours and difficult to compare, but all too soon your shoes are likely to look dated in comparison with the new fashions. On the other hand this study does suggest that if our purchases go badly, there’s probably little to choose between experiences and possessions, with the less materialistic left slightly happier with their material purchases. This may be because unhappy experiences live longer in the mind than purchases that turn out badly. Of course this study only compared material purchases with experiential purchases because, after all, this is the Journal of Consumer Research . But what about comparing material purchases with totally free experiences like a walk in the park, an afternoon spent lolling by the river or chatting with friends? In these cash-strapped times it’s worth remembering that free experiences may well make us happier than possessions, it’s just that with less money we can’t hand the responsibility for our entertainment to others (restaurants, theatres, films etc.) but have to be more creative ourselves. [Image credit: catfunt & luchilu ]

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How to Choose Between Experiential and Material Purchases

More on propranolol – the drug that doesn’t erase memories [Not Exactly Rocket Science]

February 17, 2009 in Blogs, Brain & Behaviour by BrainAndBehaviour

The mainstream media are just queuing up to fail in their reporting of the propranolol story from a couple of days ago. To reiterate: Propranolol is commonly used to treat high blood pressure and prevent migraines in children. But Merel Kindt and colleagues from the University of Amsterdam have found that it can do much more. By giving it to people before they recalled a scary memory about a spider, they could erase the fearful response it triggered. The critical thing about the study is that the entire memory hadn’t been erased in a typical sci-fi way. Kindt had trained the volunteers to be fearful of spidery images by pairing them with electric shocks. Even after they’d been given propranolol, they still expected to receive a shock when they saw a picture of a spider – they just weren’t afraid of the prospect. The drug hadn’t so much erased their memories, as dulled their emotional sting. It’s more like removing all the formatting from a Word document than deleting the entire file. The drug is not a ” memory-wiping pill ” (Guardian). It cannot “erase bad/painful memories” ( Sun / Fox News / Metro / Daily Mail ) and it won’t give you a ” spotless mind ” (Scotsman). Perhaps it’s unsurprising given that massive wire agencies said similar things. The Press Association led with claims that the drug can ” erase fearful memories “. Reuters at least said more cautiously that it was a ” step towards erasing bad memories “. To quote the person who actually did the research (and thanks Merel for chiming in on the earlier post):  “There was no memory erasure, just elimination of the fearful response.” The problem with all of this, of course, is that people have straw-manned the research and are falling over themselves to publish trite editorials that (a) are irrelevant to the actual study and (b) serve to stoke public outrage over an ethical dilemma of their own concoction. There are exceptions. The Boston Globe got it right and has a brilliant bit at the end that lays out in four simple sentences the bottom line, cautions, what’s next, and where the research was published. It has however accompanied the article with an incongruous photo of a koala, presumably some sort of mix-up with the Australian bushfire story. The mental health charity MIND released a long and well-considered statement , which showed that they had actually read the paper and understood the science. The charity’s CEO, Paul Farmer, said: “This is fascinating research that could transform the treatment for phobias and post traumatic stress disorder. Around 10 million people in the UK have a phobia and about 3.5% of the population will be affected by post traumatic stress disorder at some point yet our understanding of how to treat these conditions is still limited. While we welcome any advancement in this field we should also exercise caution before heralding this as a miracle cure. “Eradicating emotional responses is clearly an area we would need to be very careful about. It could affect people’s ability to respond to dangerous situations in the future and could even take away people’s positive memories. We would not want to see an ‘accelerated Alzheimer’s’ approach. “We still have limited research on how to treat complex mental health problems, with the focus often on pharmacological solutions. Drugs are a somewhat sledgehammer approach and can have unintended consequences. We know from other psychiatric drugs, for example antipsychotics and antidepressants, that individuals react in hugely varied ways to treatments and are often vulnerable to unpleasant side effects. “We would need to see much more research into the risks and benefits into this treatment before it becomes a reality.” All of that was culled by the BBC into the following: But British experts questioned the ethics of tampering with the mind. Paul Farmer, chief executive of mental health charity Mind, said he was concerned about the “fundamentally pharmacological” approach to people with problems such as phobias and anxiety. He said the procedure might also alter good memories and warned against an “accelerated Alzheimer’s” approach. Do you think it carries the same meaning or sense? Read the comments on this post…

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More on propranolol – the drug that doesn’t erase memories [Not Exactly Rocket Science]

Men, their perception of women, and their tools [Dr. Joan Bushwell's Chimpanzee Refuge]

February 17, 2009 in Blogs, Brain & Behaviour by BrainAndBehaviour

Research out of Princeton University and noted at this past weekend’s annual AAAS meeting gives weight to an idea that cognitive and social scientists have tentatively considered for years: Given sufficient provocation, men view women as sex objects. Men are more likely to think of women as objects if they have looked at sexy pictures of females beforehand, psychologists said yesterday. Researchers used brain scans to show that when straight men looked at pictures of women in bikinis, areas of the brain that normally light up in anticipation of using tools, like spanners and screwdrivers, were activated. Scans of some of the men found that a part of the brain associated with empathy for other peoples’ emotions and wishes shut down after looking at the pictures. Susan Fiske, a psychologist at Princeton University in New Jersey, said the changes in brain activity suggest sexy images can shift the way men perceive women, turning them from people to interact with, to objects to act upon. This makes perfect sense, given that when males view pictures of NASCAR events, daffodils, and human waste, anecdotal evidence suggests that they are inclined to think of not only various power tools, but also limitless varieties of copulatory activity. In the study, Fiske’s team put straight men into an MRI brain scanner and showed them images of either clothed men and women, or more scantily clad men and women. When they took a memory test afterwards, the men best remembered images of bikini-clad women whose heads had been digitally removed. This is merely a symbolic leveling of the playing field. If men in lust-struck states are operating without benefit of their brains, then it is only just that the objects of their lust be rendered similarly decerebrate. In the final part of the study, Fiske asked the men to fill in a questionnaire that was used to assess how sexist they were. The brain scans showed that men who scored highest had very little activity in the prefrontal cortex and other brain regions that are involved with understanding another person’s feelings and intentions. “They’re reacting to these women as if they’re not fully human,” Fiske said. “Not fully human” is as likely to mean “superhuman” as “subhuman,” correct? Looks like further research is needed . Read the comments on this post…

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Men, their perception of women, and their tools [Dr. Joan Bushwell's Chimpanzee Refuge]

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Leaders Emerge by Talking First and Most Often

February 16, 2009 in Blogs, PsyBlog by PsyBlog

Put some random people in a group, give them a task and soon enough a leader will emerge. What is it about that person that makes others grant them the honour of being in charge? New insight comes from a study published in Personality and Social Psychology , which suggests that leaders emerge through a combination of their own outspoken behaviour, and how this outspoken behaviour is perceived by others. In two studies Anderson and Kilduff (2009) from the University of California, Berkeley, looked at how dominant individuals in a group were perceived by others in the group. Perceived competence is important because, everything else being equal, it’s very difficult to become a leader if everyone in the group thinks that person is a dunce, even if they are extremely dominant. But what Anderson and Kilduff’s research showed is that there is a big gap between the actual competence of leaders and the way in which they are perceived by the others. In the second of two studies Anderson and Kilduff had participants attempting a series of maths problems in competition with another group. The groups were videotaped and the behaviour of their members carefully examined. They found that dominant participants tended to offer more suggestions to the group, and that these individuals were perceived by the group, plus those observing the group, as the most competent. Crucially, though, the study showed that not only did a leader’s dominant behaviour of itself encourage others to see that person as competent, but this was true even though their suggestions to the group were no better, or even worse than others. In reality the leaders did not always make the best contribution to the task, but their voices were usually heard first and most often. This study suggests leaders emerge through more subtle processes than the word ‘dominance’ might imply. Rather than brow-beating or bullying others into submission, leaders-in-waiting effectively signal their competence to the group by making greater verbal contributions to discussions. Others then assume that their greater contribution will mean their group will be more likely to succeed. Outside of the laboratory, of course, money and power has more to do with who leads organisations like corporations or nations. In reality groups of people don’t start on egalitarian terms and people don’t always ‘emerge’ from groups of their peers on the basis of who shouts loudest and longest. But this study does tell us something useful about more informal, everyday groups similar to those studied in this research. » See also: 7 Reasons Leaders Fail . [Image credit: Nod Young ]

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Leaders Emerge by Talking First and Most Often

Diet Soda [The Frontal Cortex]

February 11, 2009 in Blogs, Brain & Behaviour by BrainAndBehaviour

One of the perverse pleasures of spending too much time in airports is getting to people watch. I put on my “anthropologist from Mars” glasses and pass the time by staring at strangers, watching what they eat, read and how they struggle to nap in uncomfortable positions. This morning, while waiting on a very delayed plane in the Portland airport, I watched a woman perform yoga by the gate. But if I really were an anthropologist from Mars I’d be most puzzled by something else that people in airports do: drink lots of diet soda. I write this in the San Francisco airport, where I’m sitting on a bench with five other people, all of whom are sipping some sort of beverage with artificial sweetener in it, from Diet Snapple to Pepsi One. This is a bizarre ritual, no? We’re deliberating duping our tongue, enjoying the illusion of sweetness without the thing that the sweetness is supposed to represent: metabolic energy. What I find most ironic about these diet colas is that there’s good evidence that fake sugar actually leads to weight gain. Consider this recent paper in Behavioral Neuroscience, which found that rats fed artificial sweeteners gained more weight than rats fed actual sugar: Animals may use sweet taste to predict the caloric contents of food. Eating sweet noncaloric substances may degrade this predictive relationship, leading to positive energy balance through increased food intake and/or diminished energy expenditure. Adult male Sprague-Dawley rats were given differential experience with a sweet taste that either predicted increased caloric content (glucose) or did not predict increased calories (saccharin). We found that reducing the correlation between sweet taste and the caloric content of foods using artificial sweeteners in rats resulted in increased caloric intake, increased body weight, and increased adiposity, as well as diminished caloric compensation and blunted thermic responses to sweet-tasting diets. These results suggest that consumption of products containing artificial sweeteners may lead to increased body weight and obesity by interfering with fundamental homeostatic, physiological processes. There’s also some tentative evidence of the same effect in humans: Splenda is not satisfying–at least according to the brain. A new study found that even when the palate cannot distinguish between the artificial sweetener and sugar, our brain knows the difference. At the University of California, San Diego, 12 women underwent functional MRI while sipping water sweetened with either real sugar (sucrose) or Splenda (sucralose). Sweeteners, real or artificial, bind to and stimulate receptors on the taste buds, which then signal the brain via the cranial nerve. Although both sugar and Splenda initiate the same taste and pleasure pathways in the brain–and the subjects could not tell the solutions apart–the sugar activated pleasure-related brain regions more extensively than the Splenda did. In particular, “the real thing, the sugar, elicits a much greater response in the insula,” says the study’s lead author, psych ia trist Guido Frank, now at the Univer sity of Colorado at Denver. The insula, involved with taste, also plays a role in enjoyment by connecting regions in the reward system that encode the sensation of pleasantness. The essential lesson is that the brain doesn’t like being tricked. When you give us sweetness without the caloric energy, we end up craving calories more than ever. Read the comments on this post…

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Diet Soda [The Frontal Cortex]

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Women’s Makeup Draws 33% More Men

February 8, 2009 in Blogs, PsyBlog by PsyBlog

Painting of the face and body has a history dating back at least 10,000 years. According to Pliny the Elder even 2,000 years ago the Romans were using natural products in ways we would instantly recognise: they had rouge, deodorants, hair dye, wrinkle removers, breath fresheners and much more. Over the years those using cosmetics have attracted admiring glances from others for all sorts of reasons – including ritualistic and honorific – but often, especially in modern times, the context has been sexual. But does the application of these products make any difference to the way other people behave? While it might affect perceptions both positively and negatively, does it actually encourage others to make the first move? A direct approach Now some answers come in a new study by social psychologist Nicolas Geugen ( Geugen, 2008 ). In his experiment, reported in the North American Journal of Psychology , Geugen had two young women sit in a bar in France, in the first condition with makeup on, and in the second condition with their faces simply cleaned and moisturised. Then they waited for men to chat them up. When a man tried to start a conversation (nonverbal behaviours didn’t count) one of the women signalled to experimental confederates that contact had been made by crossing her arms. Then she politely turned the man down, saying they were waiting for friends to arrive. This procedure was repeated over 60 observational periods of one hour in two different bars. Here’s what happened: No makeup condition : The first man ‘made contact’ with the two women after an average of 23 minutes, and thereafter they were hit on 1.5 times per hour. With makeup condition : The first man tried it on after only 17 minutes and the average number of chancers per hour was 2. These results certainly suggest the makeup was effective in changing men’s behaviour, with one third more men approaching the two women when they were made-up. But while this study is good fun, there are a couple of problems the authors acknowledge. First wearing makeup could have given the two women more confidence, subtly changing their behaviour and encouraging men to approach. This may well have accounted for the men’s behaviour instead of the makeup. Second it may be difficult to generalise as the study was carried out in France – men in very different cultures might respond in quite another way. How does makeup work? These aside, though, the other interesting question it raises is exactly how makeup works. While makeup seems to work by increasing perceived attractivity, it can also signal a willingness to interact or even availability. Further, cosmetics can send signals about status: one study published in the International Journal of Cosmetics Science has found that people judge women wearing cosmetics as higher earners with more prestigious jobs ( Nash et al., 2006 ). Researchers have even looked at which components of makeup are most attractive to men. A recent study has found that eye makeup has the most powerful effect on female perceived attractivity, followed by foundation; lipstick, surprisingly, was found to have little independent effect ( Mulhern et al., 2003 ). Nowadays, though, discussions about makeup seem tame, even quaint, considering the more radical methods people use for changing their appearance, like cosmetic surgery. But one aspect is still cutting-edge: men wearing makeup. So, I wonder how long it will be until Nicolas Geugen is returning to these bars on the west coast of France, this time with two young men wearing makeup, ready to see who approaches? [Image credit: Uh ... Bob ]

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Women’s Makeup Draws 33% More Men

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Women’s Makeup Draws 33% More Men

February 8, 2009 in Blogs, PsyBlog by PsyBlog

Painting of the face and body has a history dating back at least 10,000 years. According to Pliny the Elder even 2,000 years ago the Romans were using natural products in ways we would instantly recognise: they had rouge, deodorants, hair dye, wrinkle removers, breath fresheners and much more. Over the years those using cosmetics have attracted admiring glances from others for all sorts of reasons – including ritualistic and honorific – but often, especially in modern times, the context has been sexual. But does the application of these products make any difference to the way other people behave? While it might affect perceptions both positively and negatively, does it actually encourage others to make the first move? A direct approach Now some answers come in a new study by social psychologist Nicolas Geugen ( Geugen, 2008 ). In his experiment, reported in the North American Journal of Psychology , Geugen had two young women sit in a bar in France, in the first condition with makeup on, and in the second condition with their faces simply cleaned and moisturised. Then they waited for men to chat them up. When a man tried to start a conversation (nonverbal behaviours didn’t count) one of the women signalled to experimental confederates that contact had been made by crossing her arms. Then she politely turned the man down, saying they were waiting for friends to arrive. This procedure was repeated over 60 observational periods of one hour in two different bars. Here’s what happened: No makeup condition : The first man ‘made contact’ with the two women after an average of 23 minutes, and thereafter they were hit on 1.5 times per hour. With makeup condition : The first man tried it on after only 17 minutes and the average number of chancers per hour was 2. These results certainly suggest the makeup was effective in changing men’s behaviour, with one third more men approaching the two women when they were made-up. But while this study is good fun, there are a couple of problems the authors acknowledge. First wearing makeup could have given the two women more confidence, subtly changing their behaviour and encouraging men to approach. This may well have accounted for the men’s behaviour instead of the makeup. Second it may be difficult to generalise as the study was carried out in France – men in very different cultures might respond in quite another way. How does makeup work? These aside, though, the other interesting question it raises is exactly how makeup works. While makeup seems to work by increasing perceived attractivity, it can also signal a willingness to interact or even availability. Further, cosmetics can send signals about status: one study published in the International Journal of Cosmetics Science has found that people judge women wearing cosmetics as higher earners with more prestigious jobs ( Nash et al., 2006 ). Researchers have even looked at which components of makeup are most attractive to men. A recent study has found that eye makeup has the most powerful effect on female perceived attractivity, followed by foundation; lipstick, surprisingly, was found to have little independent effect ( Mulhern et al., 2003 ). Nowadays, though, discussions about makeup seem tame, even quaint, considering the more radical methods people use for changing their appearance, like cosmetic surgery. But one aspect is still cutting-edge: men wearing makeup. So, I wonder how long it will be until Nicolas Geugen is returning to these bars on the west coast of France, this time with two young men wearing makeup, ready to see who approaches? [Image credit: Uh ... Bob ]

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Women’s Makeup Draws 33% More Men

Chapter 12: Geographical Distribution, continued [Blogging the Origin]

February 6, 2009 in Blogs, Developing Intelligence by ScienceBlog

Back when I started this, I remarked that one of the reasons I hadn’t read the Origin was that I couldn’t imagine it being essential to a grasp of contemporary science. Regarding evolution, I think you could still make a case for this. But in other ways, that statement shows that you really shouldn’t opine on topics you know nothing about. Specifically, I’m talking about ecology (by which, just to be clear, I mean the study of the interactions of living things with each other and their environment, rather than ‘nature’ or ‘environmentalism’). It’s been said that all European philosophy is a series of footnotes to Plato. Well, all ecology is a series of footnotes to Darwin. Read the rest of this post… | Read the comments on this post…

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Chapter 12: Geographical Distribution, continued [Blogging the Origin]